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β-arrestin-2 expressed in mast cells regulates ciprofloxacin-induced pseudo-allergy and IgE-mediated anaphylaxis
The adapter protein β-arrestin2 inhibits Mrgprb2 and FcεRI-mediated mast cell degranulation to attenuate pseudo-allergy and anaphylaxis. Thus, targeting β-arrestin2 in mast cells could provide novel therapeutic options for modulating pseudo-allergy and anaphylaxis.
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| Publicado no: | J Allergy Clin Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688937/ https://ncbi.nlm.nih.gov/pubmed/31077686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.04.024 |
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