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Divergent Synthesis of Organophosphate [(11)C]VX- and [(11)C]Sarin-Surrogates from a Common Set of Starting Materials

Radiolabeled 1-[(11)C]ethyl, 4-nitrophenyl methylphosphonate (VX-surrogate) and 2-[(11)C]-propanyl, 4-nitrophenyl methylphosphonate (sarin surrogate) were developed as organophosphate (OP) tracers. The [(11)C]ethyl- and [(11)C]isopropyl-iodide radiolabeled synthons were obtained by temperature contr...

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Foilsithe in:Appl Radiat Isot
Main Authors: Hayes, Thomas R., Blecha, Joseph E., Thompson, Charles M., Gerdes, John M., VanBrocklin, Henry F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688906/
https://ncbi.nlm.nih.gov/pubmed/31202183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2019.05.033
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