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Impact of Itga2-Gp6-double collagen receptor deficient mice for bone marrow megakaryocytes and platelets

The two main collagen receptors on platelets, GPVI and integrin α2β1, play an important role for the recognition of exposed collagen at sites of vessel injury, which leads to platelet activation and subsequently stable thrombus formation. Both receptors are already expressed on megakaryocytes, the p...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Semeniak, Daniela, Faber, Kristina, Öftering, Patricia, Manukjan, Georgi, Schulze, Harald
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688823/
https://ncbi.nlm.nih.gov/pubmed/31398205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216839
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