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The Nimodipine-Sparing Effect of Perioperative Dexmedetomidine Infusion During Aneurysmal Subarachnoid Hemorrhage: A Prospective, Randomized, Controlled Trial

Background: Nimodipine can block the influx of calcium into the vascular smooth muscle cell and prevent secondary ischemia in patients with aneurysmal subarachnoid hemorrhage. However, the reduction of blood pressure after long-term intravenous administration of nimodipine has been associated with n...

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Publicado en:Front Pharmacol
Main Authors: Ren, Chunguang, Gao, Jian, Xu, Guang jun, Xu, Huiying, Liu, Guoying, Liu, Lei, Zhang, Liyong, Cao, Jun-Li, Zhang, Zongwang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688624/
https://ncbi.nlm.nih.gov/pubmed/31427968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00858
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