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The Nimodipine-Sparing Effect of Perioperative Dexmedetomidine Infusion During Aneurysmal Subarachnoid Hemorrhage: A Prospective, Randomized, Controlled Trial

Background: Nimodipine can block the influx of calcium into the vascular smooth muscle cell and prevent secondary ischemia in patients with aneurysmal subarachnoid hemorrhage. However, the reduction of blood pressure after long-term intravenous administration of nimodipine has been associated with n...

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Publicat a:Front Pharmacol
Autors principals: Ren, Chunguang, Gao, Jian, Xu, Guang jun, Xu, Huiying, Liu, Guoying, Liu, Lei, Zhang, Liyong, Cao, Jun-Li, Zhang, Zongwang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688624/
https://ncbi.nlm.nih.gov/pubmed/31427968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00858
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