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FLT3-ITD gets by with a little help from PRMT1
In this issue of Blood, He et al discuss their discovery that methylation of fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) at arginines 972 and 973 by protein arginine N-methyltransferase 1 (PRMT1) potentiates oncogenic signaling and that inhibition of PRMT1 can improve the effic...
Kaydedildi:
| Yayımlandı: | Blood |
|---|---|
| Yazar: | |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688432/ https://ncbi.nlm.nih.gov/pubmed/31395582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001876 |
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