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Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum

BACKGROUND: Asthma is a heterogeneous disease and understanding this heterogeneity will enable the realisation of precision medicine. We sought to compare the sputum and serum inflammatory profiles in moderate-to-severe asthma during stable disease and exacerbation events. METHODS: We recruited 102...

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Publicado en:BMC Pulm Med
Main Authors: Ghebre, Michael A., Pang, Pee Hwee, Desai, Dhananjay, Hargadon, Beverley, Newby, Chris, Woods, Joanne, Rapley, Laura, Cohen, Suzanne E., Herath, Athula, Gaillard, Erol A., May, Richard D., Brightling, Chris E.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688375/
https://ncbi.nlm.nih.gov/pubmed/31395050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-019-0906-7
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