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Elevated Sputum Interleukin-5 and Submucosal Eosinophilia in Obese Individuals with Severe Asthma

Rationale: The relationship between airway inflammation and obesity in severe asthma is poorly understood. Objectives: We sought to determine the relationship between sputum mediator profiles and the distribution of eosinophilic inflammation and obesity in people with severe asthma. Methods: Clinica...

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Autors principals: Desai, Dhananjay, Newby, Christopher, Symon, Fiona A., Haldar, Pranabashis, Shah, Sachil, Gupta, Sumit, Bafadhel, Mona, Singapuri, Amisha, Siddiqui, Salman, Woods, Joanne, Herath, Athula, Anderson, Ian K., Bradding, Peter, Green, Ruth, Kulkarni, Nita, Pavord, Ian, Marshall, Richard P., Sousa, Ana R., May, Richard D., Wardlaw, Andrew J., Brightling, Chris E.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826183/
https://ncbi.nlm.nih.gov/pubmed/23590263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201208-1470OC
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