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Is it time to change the reference genome?

The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating a few constraints. In the following opinion, we outline the history, properties, and pitfalls of the current human reference genome. In a few illustrative analyses,...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Ballouz, Sara, Dobin, Alexander, Gillis, Jesse A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688217/
https://ncbi.nlm.nih.gov/pubmed/31399121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1774-4
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