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Is it time to change the reference genome?

The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating a few constraints. In the following opinion, we outline the history, properties, and pitfalls of the current human reference genome. In a few illustrative analyses,...

詳細記述

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書誌詳細
出版年:Genome Biol
主要な著者: Ballouz, Sara, Dobin, Alexander, Gillis, Jesse A.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688217/
https://ncbi.nlm.nih.gov/pubmed/31399121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1774-4
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