ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

BACKGROUND: KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin states. ZF...

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Détails bibliographiques
Publié dans:Epigenetics Chromatin
Auteurs principaux: Shi, Hui, Strogantsev, Ruslan, Takahashi, Nozomi, Kazachenka, Anastasiya, Lorincz, Matthew C., Hemberger, Myriam, Ferguson-Smith, Anne C.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688207/
https://ncbi.nlm.nih.gov/pubmed/31399135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0295-4
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