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Defect Assisted Permeation Through a Phospholipid Membrane: Experimental and Computational Study of the Peptide WKW

We investigate membrane permeation by the peptide WKW that is amidated at its C-terminus and therefore carries a positive charge of +2. To facilitate an efficient calculation, we introduce a novel set of simple coarse variables that measure permeation depth and membrane distortion. The phospholipid...

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Publicat a:J Phys Chem B
Autors principals: Fathizadeh, Arman, Kogan, Molly, Anderson, Cari M., Webb, Lauren J., Elber, Ron
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687544/
https://ncbi.nlm.nih.gov/pubmed/31304755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b05414
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