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Ion Permeation Through a Phospholipid Membrane: Transition State, Path Splitting, and Calculation of Permeability

We investigate the thermodynamics and kinetics of the permeation of a potassium ion through a phospholipid membrane. We illustrate that the conventional reaction coordinate (the position of the ion along the normal to the membrane plane) is insufficient to capture essential elements of the process....

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Fathizadeh, Arman, Elber, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467798/
https://ncbi.nlm.nih.gov/pubmed/30474968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00882
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