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A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass

A typical task arising from main effect analyses in a Genome Wide Association Study (GWAS) is to identify Single Nucleotide Polymorphisms (SNPs), in linkage disequilibrium with the observed signals, that are likely causal variants and the affected genes. The affected genes may not be those closest t...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Manduchi, Elisabetta, Hemerich, Daiane, van Setten, Jessica, Tragante, Vinicius, Harakalova, Magdalena, Pei, Jiayi, Williams, Scott M., van der Harst, Pim, Asselbergs, Folkert W., Moore, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687530/
https://ncbi.nlm.nih.gov/pubmed/31145509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22215
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