Imputed gene associations identify replicable trans‐acting genes enriched in transcription pathways and complex traits

Regulation of gene expression is an important mechanism through which genetic variation can affect complex traits. A substantial portion of gene expression variation can be explained by both local (cis) and distal (trans) genetic variation. Much progress has been made in uncovering cis‐acting expres...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Wheeler, Heather E., Ploch, Sally, Barbeira, Alvaro N., Bonazzola, Rodrigo, Andaleon, Angela, Fotuhi Siahpirani, Alireza, Saha, Ashis, Battle, Alexis, Roy, Sushmita, Im, Hae Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687523/
https://ncbi.nlm.nih.gov/pubmed/30950127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22205
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