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Effects of Refolding on Large-Scale RNA Structure

Understanding RNA-mediated functions requires detailed characterization of the underlying RNA structure. In many cases, structure probing experiments are performed on RNA that has been “refolded” in some way, which may cause the conformation to differ from the native RNA. We used SHAPE-MaP to probe...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Dethoff, Elizabeth A., Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687061/
https://ncbi.nlm.nih.gov/pubmed/31268687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01219
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