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P450 Monooxygenases Enable Rapid Late‐Stage Diversification of Natural Products via C−H Bond Activation

The biological potency of natural products has been exploited for decades. Their inherent structural complexity and natural diversity might hold the key to efficiently address the urgent need for the development of novel pharmaceuticals. At the same time, it is that very complexity, which impedes ne...

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Detalhes bibliográficos
Publicado no:ChemCatChem
Autor principal: Fessner, Nico D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686969/
https://ncbi.nlm.nih.gov/pubmed/31423290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cctc.201801829
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