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Quantitative proteomics reveals novel interaction partners of Rac1 in pancreatic β-cells: Evidence for increased interaction with Rac1 under hyperglycemic conditions()

Rac1, a small G protein, regulates physiological insulin secretion from the pancreatic β-cell. Interestingly, Rac1 has also been implicated in the onset of metabolic dysfunction of the β-cell under the duress of hyperglycemia (HG). This study is aimed at the identification of interaction partners of...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Endocrinol
Autori principali: Damacharla, Divyasri, Thamilselvan, Vijayalakshmi, Zhang, Xiangmin, Mestareehi, Aktham, Yi, Zhengping, Kowluru, Anjaneyulu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686664/
https://ncbi.nlm.nih.gov/pubmed/31202817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.110489
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