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ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis

BACKGROUND: Pancreatic cancer is a highly lethal malignancy with poor prognosis. Anillin (ANLN), an actin binding protein, is upregulated and plays an important role in many malignant tumors. However, the precise role of ANLN in pancreatic cancer remains unclear. METHODS: The expression of ANLN and...

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Foilsithe in:J Exp Clin Cancer Res
Main Authors: Wang, Anbin, Dai, Haisu, Gong, Yi, Zhang, Chengcheng, Shu, Junjie, Luo, Yuandeng, Jiang, Yan, Liu, Wei, Bie, Ping
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686567/
https://ncbi.nlm.nih.gov/pubmed/31395079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1340-7
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