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ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis

BACKGROUND: Pancreatic cancer is a highly lethal malignancy with poor prognosis. Anillin (ANLN), an actin binding protein, is upregulated and plays an important role in many malignant tumors. However, the precise role of ANLN in pancreatic cancer remains unclear. METHODS: The expression of ANLN and...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Wang, Anbin, Dai, Haisu, Gong, Yi, Zhang, Chengcheng, Shu, Junjie, Luo, Yuandeng, Jiang, Yan, Liu, Wei, Bie, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686567/
https://ncbi.nlm.nih.gov/pubmed/31395079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1340-7
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