Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats

BACKGROUND: The adipose afferent reflex (AAR), a sympatho-excitatory reflex, can promote the elevation of sympathetic nerve activity (SNA) and blood pressure (BP). Inflammation in the paraventricular nucleus (PVN) involves sympathetic abnormality in some cardiovascular diseases such as hypertension....

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ding, Lei, Kang, Ying, Dai, Hang-Bing, Wang, Fang-Zheng, Zhou, Hong, Gao, Qing, Xiong, Xiao-Qing, Zhang, Feng, Song, Tian-Run, Yuan, Yan, Liu, Ming, Zhu, Guo-Qing, Zhou, Ye-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686415/
https://ncbi.nlm.nih.gov/pubmed/31391086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2006-0
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