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CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease of cardiopulmonary units. No cure is currently available due to an incomplete understanding of vascular remodeling. Here we identify CD146-hypoxia-inducible transcription factor 1 alpha (HIF-1α) cross-regulation as a key determin...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686016/ https://ncbi.nlm.nih.gov/pubmed/31391533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11500-6 |
| Oznake: |
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