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Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

Mammalian embryos change shape dramatically upon implantation. The cellular and molecular mechanism underlying this transition are largely unknown. Here, we show that this transition is directed by cross talk between the embryonic epiblast and the first extra-embryonic tissue, the trophectoderm. Spe...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Christodoulou, Neophytos, Weberling, Antonia, Strathdee, Douglas, Anderson, Kurt I., Timpson, Paul, Zernicka-Goetz, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686005/
https://ncbi.nlm.nih.gov/pubmed/31391456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11482-5
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