Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria

The Oxford MinION, the first commercial nanopore sequencer, is also the first to implement molecule-by-molecule real-time selective sequencing or “Read Until”. As DNA transits a MinION nanopore, real-time pore current data can be accessed and analyzed to provide active feedback to that pore. Fragmen...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Edwards, Harrison S., Krishnakumar, Raga, Sinha, Anupama, Bird, Sara W., Patel, Kamlesh D., Bartsch, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685950/
https://ncbi.nlm.nih.gov/pubmed/31391493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47857-3
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