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On top of biosynthetic gene clusters: How epigenetic machinery influences secondary metabolism in fungi

Fungi produce an abundance of bioactive secondary metabolites which can be utilized as antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are contiguously arranged in biosynthetic gene clusters (BGCs), which supports co-regulation of all genes required for any one metabol...

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Publicat a:Biotechnol Adv
Autors principals: Pfannenstiel, Brandon T., Keller, Nancy P.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685777/
https://ncbi.nlm.nih.gov/pubmed/30738111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2019.02.001
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