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On top of biosynthetic gene clusters: How epigenetic machinery influences secondary metabolism in fungi

Fungi produce an abundance of bioactive secondary metabolites which can be utilized as antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are contiguously arranged in biosynthetic gene clusters (BGCs), which supports co-regulation of all genes required for any one metabol...

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Bibliografiske detaljer
Udgivet i:Biotechnol Adv
Main Authors: Pfannenstiel, Brandon T., Keller, Nancy P.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685777/
https://ncbi.nlm.nih.gov/pubmed/30738111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2019.02.001
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