Targeted transcriptional profiling of the tumor microenvironment reveals lymphocyte exclusion and vascular dysfunction in metastatic osteosarcoma

Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients yet little is known about the microenvironment that supports this aggressive disease. We have used targeted gene expression profiling and immunohistochemistry to characterize the microenvironment of meta...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Sorenson, Laurie, Fu, Yanfen, Hood, Tressa, Warren, Sarah, McEachron, Troy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685511/
https://ncbi.nlm.nih.gov/pubmed/31428529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1629779
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