CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents. The present study investigated the expression of Cytochrome P-450 (CYP) genes: CYP1A2, CYP3A4 and CYP3A5 by qRT-PCR in 135 specimens obtained from OS patients, including biopsy (pre-chemotherapy), tumor resected i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Trujillo-Paolillo, Alini, Tesser-Gamba, Francine, Petrilli, Antonio Sergio, de Seixas Alves, Maria Teresa, Filho, Reynaldo Jesus Garcia, de Oliveira, Renato, de Toledo, Silvia Regina Caminada
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503551/
https://ncbi.nlm.nih.gov/pubmed/28404946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15869
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