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Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses

As the prevalence of Alzheimer disease (AD) continues to rise unabated, new models have been put forth to improve our understanding of this devastating condition. Although individual models may have their merits, integrated models may prove more valuable. Indeed, the reliable failures of monotherapi...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Norwitz, Nicholas G., Mota, Adrian Soto, Norwitz, Sam G., Clarke, Kieran
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685392/
https://ncbi.nlm.nih.gov/pubmed/31417394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00184
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