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Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses

As the prevalence of Alzheimer disease (AD) continues to rise unabated, new models have been put forth to improve our understanding of this devastating condition. Although individual models may have their merits, integrated models may prove more valuable. Indeed, the reliable failures of monotherapi...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Norwitz, Nicholas G., Mota, Adrian Soto, Norwitz, Sam G., Clarke, Kieran
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685392/
https://ncbi.nlm.nih.gov/pubmed/31417394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00184
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