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Designing gene panels for tumor mutational burden estimation: the need to shift from ‘correlation’ to ‘accuracy’
Tumor mutational burden (TMB) assessment is at the forefront in precision medicine. The TMB could represent a biomarker for immune checkpoint inhibitors (ICIs) responses. Whole exome sequencing (WES) is the gold standard to derive the TMB; while targeted next-generation sequencing panels might be mo...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685228/ https://ncbi.nlm.nih.gov/pubmed/31387639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0681-2 |
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