The Tumor Mutational Burden of Chinese Advanced Cancer Patients Estimated by a 381-cancer-gene Panel

Purpose: Tumor mutational burden (TMB) calculated by whole-exome sequencing (WES) is proved to be effective to predict the clinical benefit of immune checkpoint blockades. However, WES is not commonly used in China. We aimed to determine if a 381-caner-gene panel (CGP) could be used to estimate TMB,...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Zhuang, Wu, Ma, Junxun, Chen, Xudong, Wang, Guoqiang, Lu, Jing, Chen, Yanan, Dong, Hua, Cai, Shangli, Zhang, Yuzi, Zhao, Xiaochen, Zhu, Youcai, Xu, Chunwei, Huang, Yunjian, Huang, Zhangzhou, Zhu, Xiaofeng, Jiang, Hong, Wang, Zhijie
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036723/
https://ncbi.nlm.nih.gov/pubmed/30026825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.24932
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