Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies

4-1BB (CD137) is an inducible costimulatory receptor that promotes expansion and survival of activated T cells; and IgG-based 4-1BB-agonistic monoclonal antibodies exhibited potent antitumor activity in clinical trials. However, the clinical development of those antibodies is restricted by major off...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Mikkelsen, Kasper, Harwood, Seandean Lykke, Compte, Marta, Merino, Nekane, Mølgaard, Kasper, Lykkemark, Simon, Alvarez-Mendez, Ana, Blanco, Francisco J., Álvarez-Vallina, Luis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685135/
https://ncbi.nlm.nih.gov/pubmed/31417564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01791
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller