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Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma
PIN1 is a phosphorylation-dependent peptidyl-prolyl cis/trans isomerase, overexpressed in many cancers, including melanoma. Our immunohistochemistry data of melanoma patient tissue underline the up-regulation of PIN1 in metastases. Here, we demonstrate important functions of PIN1 and its selective a...
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| Udgivet i: | Am J Transl Res |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
e-Century Publishing Corporation
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684922/ https://ncbi.nlm.nih.gov/pubmed/31396346 |
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