Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children

High hyperdiploidy (HD) is the most common cytogenetic subtype of childhood acute lymphoblastic leukemia (ALL), and a higher incidence of HD has been reported in ALL patients with congenital cancer syndromes. We assessed the frequency of predisposing germline mutations in 57 HD-ALL patients from the...

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Publicado no:Genes Chromosomes Cancer
Main Authors: de Smith, Adam J., Lavoie, Geneviève, Walsh, Kyle M., Aujla, Sumeet, Evans, Erica, Hansen, Helen M., Smirnov, Ivan, Kang, Alice Y., Zenker, Martin, Ceremsak, John J., Stieglitz, Elliot, Muskens, Ivo S., Roberts, William, McKean-Cowdin, Roberta, Metayer, Catherine, Roux, Philippe P., Wiemels, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684857/
https://ncbi.nlm.nih.gov/pubmed/31102422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22765
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