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Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro

The aim of the present study was to elucidate the in vitro short-term (2-h) and longer-term (24-h) effects of hyperosmolar media (500 and 680 mOsm/L) on intestinal epithelial cells using the human colonocyte Caco-2 cell line model. We found that a hyperosmolar environment slowed down cell proliferat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grauso, Marta, Lan, Annaïg, Andriamihaja, Mireille, Bouillaud, Frédéric, Blachier, François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684637/
https://ncbi.nlm.nih.gov/pubmed/31388052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47851-9
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