Mitochondrial function controls intestinal epithelial stemness and proliferation

Control of intestinal epithelial stemness is crucial for tissue homeostasis. Disturbances in epithelial function are implicated in inflammatory and neoplastic diseases of the gastrointestinal tract. Here we report that mitochondrial function plays a critical role in maintaining intestinal stemness a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Berger, Emanuel, Rath, Eva, Yuan, Detian, Waldschmitt, Nadine, Khaloian, Sevana, Allgäuer, Michael, Staszewski, Ori, Lobner, Elena M., Schöttl, Theresa, Giesbertz, Pieter, Coleman, Olivia I., Prinz, Marco, Weber, Achim, Gerhard, Markus, Klingenspor, Martin, Janssen, Klaus-Peter, Heikenwalder, Mathias, Haller, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080445/
https://ncbi.nlm.nih.gov/pubmed/27786175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13171
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