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Chromatically independent, two-color uncaging of glutamate and GABA with one- or two-photon excitation.

Caged compounds enable fast, light-induced, and spatially-defined application of bioactive molecules to cells. Covalent attachment of a caging chromophore to a crucial functionality of a biomolecule renders it inert, while short pulses of light release the caged molecule in its active form. Caged ne...

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Publicat a:Methods Enzymol
Autors principals: Passlick, Stefan, Ellis-Davies, Graham C.R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684293/
https://ncbi.nlm.nih.gov/pubmed/31370929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.05.003
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