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Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection

The ability of Staphylococcus aureus and other pathogens to consume glucose is critical during infection. However, glucose consumption increases the cellular demand for manganese sensitizing S. aureus to host-imposed manganese starvation. The current investigations were undertaken to elucidate how S...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Radin, Jana N., Kelliher, Jessica L., Solórzano, Paola K. Párraga, Grim, Kyle P., Ramezanifard, Rouhallah, Slauch, James M., Kehl-Fie, Thomas E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684088/
https://ncbi.nlm.nih.gov/pubmed/31344131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007971
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