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The Metallophore Staphylopine Enables Staphylococcus aureus To Compete with the Host for Zinc and Overcome Nutritional Immunity

During infection, the host sequesters essential nutrients, such as zinc, to combat invading microbes. Despite the ability of the immune effector protein calprotectin to bind zinc with subpicomolar affinity, Staphylococcus aureus is able to successfully compete with the host for zinc. However, the zi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Grim, Kyle P., San Francisco, Brian, Radin, Jana N., Brazel, Erin B., Kelliher, Jessica L., Párraga Solórzano, Paola K., Kim, Philip C., McDevitt, Christopher A., Kehl-Fie, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666155/
https://ncbi.nlm.nih.gov/pubmed/29089427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01281-17
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