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Random formation of G-quadruplexes in human telomere overhangs leads to a kinetic folding pattern with targetable vacant G-tracts
G-quadruplexes formed in the 3′ telomere overhang (~200 nucleotides) have shown to regulate biological functions of human telomeres. The mechanism governing the population pattern of multiple telomeric G-quadruplexes is yet to be elucidated inside the telomeric overhang in a time window shorter than...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684037/ https://ncbi.nlm.nih.gov/pubmed/30480434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00957 |
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