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Binding of a Telomestatin Derivative Changes Mechanical Anisotropy of Human Telomeric G-quadruplex

Mechanical anisotropy is an essential property for biomolecules to assume structural and functional roles in mechanobiology. However, there is insufficient information on the mechanical anisotropy of ligand-biomokcule complexes. Herein, we investigated the mechanical property of individual human tel...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Main Authors: Jonchhe, Sagun, Ghimire, Chiran, Cui, Yunxi, Sasaki, Shogo, McCool, Mason, Park, Soyoung, lida, Keisuke, Nagasawa, Kazuo, Sugiyama, Hiroshi, Mao, Hanbin
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669079/
https://ncbi.nlm.nih.gov/pubmed/30476359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201811046
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