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Filamin A mediates isotropic distribution of applied force across the actin network

Cell sensing of externally applied mechanical strain through integrin-mediated adhesions is critical in development and physiology of muscle, lung, tendon, and arteries, among others. We examined the effects of strain on force transmission through the essential cytoskeletal linker talin. Using a flu...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Kumar, Abhishek, Shutova, Maria S., Tanaka, Keiichiro, Iwamoto, Daniel V., Calderwood, David A., Svitkina, Tatyana M., Schwartz, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683746/
https://ncbi.nlm.nih.gov/pubmed/31315944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201901086
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