Apoptotic Cell–Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN

BACKGROUND: Myeloperoxidase (MPO)-ANCA–associated GN is a significant cause of renal failure. Manipulating autoimmunity by inducing regulatory T cells is potentially a more specific and safer therapeutic option than conventional immunosuppression. METHODS: To generate MPO-specific regulatory T cells...

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Udgivet i:J Am Soc Nephrol
Main Authors: Gan, Poh-Yi, Godfrey, Andrea S., Ooi, Joshua D., O’Sullivan, Kim-Maree, Oudin, Virginie, Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2019
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683705/
https://ncbi.nlm.nih.gov/pubmed/31337690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018090955
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