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PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1

BACKGROUND: Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and improve survival. Phospholipase C (PLC)ε is a regulator of...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Fan, Jiaxin, Fan, Yanru, Wang, Xiao, Niu, Lingfang, Duan, Limei, Yang, Jinxiao, Li, Luo, Gao, Yingying, Wu, Xiaohou, Luo, Chunli
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683382/
https://ncbi.nlm.nih.gov/pubmed/31383001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1323-8
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