PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1

BACKGROUND: Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and improve survival. Phospholipase C (PLC)ε is a regulator of...

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Bibliografiska uppgifter
I publikationen:J Exp Clin Cancer Res
Huvudupphovsmän: Fan, Jiaxin, Fan, Yanru, Wang, Xiao, Niu, Lingfang, Duan, Limei, Yang, Jinxiao, Li, Luo, Gao, Yingying, Wu, Xiaohou, Luo, Chunli
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683382/
https://ncbi.nlm.nih.gov/pubmed/31383001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1323-8
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