PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1

BACKGROUND: Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and improve survival. Phospholipase C (PLC)ε is a regulator of...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Fan, Jiaxin, Fan, Yanru, Wang, Xiao, Niu, Lingfang, Duan, Limei, Yang, Jinxiao, Li, Luo, Gao, Yingying, Wu, Xiaohou, Luo, Chunli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683382/
https://ncbi.nlm.nih.gov/pubmed/31383001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1323-8
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