Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer

BACKGROUND: Trastuzumab is a drug that targets the receptor tyrosine kinase HER2 and is essential for the treatment of HER2-positive breast cancer. Resistance to the drug leads to severe consequences, including disease recurrence, tumor enlargement, and metastasis. We hypothesized that trastuzumab t...

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Veröffentlicht in:Breast Cancer Res
Hauptverfasser: Hori, Ami, Shimoda, Masafumi, Naoi, Yasuto, Kagara, Naofumi, Tanei, Tomonori, Miyake, Tomohiro, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683360/
https://ncbi.nlm.nih.gov/pubmed/31387614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1167-3
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