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Immune system development and age-dependent maintenance in Klotho-hypomorphic mice

Circulating Klotho peptide hormone has anti-aging activity and affects tissue maintenance. Hypomorphic mutant Klotho [kl/kl] mice on C57BL/6xC3H, BALB/c and 129 genetic backgrounds, show decreased Klotho expression that correlate with accelerated aging including pre-mature death due to abnormally hi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Zhu, Wandi Sandra, Naler, Lynette, Maul, Robert W., Sallin, Michelle A., Sen, Jyoti Misra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682518/
https://ncbi.nlm.nih.gov/pubmed/31386628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102121
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