1,25(OH)(2)D(3) dependent overt hyperactivity phenotype in klotho-hypomorphic mice

Klotho, a protein mainly expressed in kidney and cerebral choroid plexus, is a powerful regulator of 1,25(OH)(2)D(3) formation. Klotho-deficient mice (kl/kl) suffer from excessive plasma 1,25(OH)(2)D(3)-, Ca(2+)- and phosphate-concentrations, leading to severe soft tissue calcification and accelerat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Leibrock, Christina B., Voelkl, Jakob, Kuro-o, Makoto, Lang, Florian, Lang, Undine E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843009/
https://ncbi.nlm.nih.gov/pubmed/27109615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24879
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