Foxr2 promotes formation of CNS-embryonal tumors in a Trp53-deficient background

BACKGROUND: Embryonal tumors in the central nervous system (CNS) are primary, aggressive, and poorly differentiated pediatric brain tumors. We identified forkhead box R2 (Foxr2) as an oncogene for medulloblastoma through a transposon-based insertional mutagenesis screen. Foxr2 translocation has been...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Poh, Boonmin, Koso, Hideto, Momota, Hiroyuki, Komori, Takashi, Suzuki, Yutaka, Yoshida, Nobuaki, Ino, Yasushi, Todo, Tomoki, Watanabe, Sumiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682215/
https://ncbi.nlm.nih.gov/pubmed/30976792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz067
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